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Investigation of the stereochemistry of intermolecular conjugate additions of nucleophiles to acyclic nitrosoalkenes.

ABSTRACT: Michael-type conjugate additions of ?-chiral aldehyde-derived acyclic nitrosoalkenes have been explored using a series of carbon and hetero nucleophiles. In all cases examined, these reactions are stereoselective, leading exclusively to the anti products.

SUBMITTER: Witek JA

PROVIDER: S-EPMC3046371 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature

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Investigation of the stereochemistry of intermolecular conjugate additions of nucleophiles to acyclic nitrosoalkenes.

Witek Jason A JA Weinreb Steven M SM

Organic letters 20110204 5

Michael-type conjugate additions of γ-chiral aldehyde-derived acyclic nitrosoalkenes have been explored using a series of carbon and hetero nucleophiles. In all cases examined, these reactions are stereoselective, leading exclusively to the anti products. ...[more]

PMID: 21294528

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