Ontology highlight
ABSTRACT:
SUBMITTER: Biehs B
PROVIDER: S-EPMC3049281 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Development (Cambridge, England) 20101101 22
Paracrine Hedgehog (Hh) signaling regulates growth and patterning in many Drosophila organs. We mapped chromatin binding sites for Cubitus interruptus (Ci), the transcription factor that mediates outputs of Hh signal transduction, and we analyzed transcription profiles of control and mutant embryos to identify genes that are regulated by Hh. Putative targets that we identified included several Hh pathway components, mostly previously identified targets, and many targets that are novel. Every Hh ...[more]