1-[2-(4-Nitro-phen-yl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetra-hydro-quinolin-4-yl]pyrrolidin-2-one monohydrate.

ABSTRACT: The title compound, C(28)H(24)N(4)O(4)·H(2)O, crystallizes with two organic mol-ecules and two solvent water mol-ecules in the asymmetric unit. The most obvious difference between the mol-ecules is the torsion angles between the isoxazole ring and the benzene and phenyl rings [47.0?(2)/56.4?(2) and 33.3?(2)/11.0?(2)°, respectively]. Another important difference is observed in the rotation of the nitro group with respect to the phenyl groups [3.5?(6) and 31.1?(6)°]. The pyrrolidinone fragment is cis oriented with respect to the 4-nitro-phenyl fragment. In the crystal, mol-ecules are linked into centrosymmetric R(4) (2)(8) and R(4) (4)(20) motifs by O-H?O and N-H?O inter-actions.

SUBMITTER: Gutierrez M 

PROVIDER: S-EPMC3050245 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature