Ontology highlight
ABSTRACT:
SUBMITTER: Tang J
PROVIDER: S-EPMC3050490 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Tang Jing J Trahan Daniel W DW Doyle Patrick S PS
Macromolecules 20100301 6
We experimentally investigate the influence of slit-like confinement on the coil-stretch transition of single DNA molecules in a homogeneous planar elongational electric field. We observe a more gradual coil-stretch transition characterized by two distinct critical strain rates for DNA in confinement, different from the unconfined case where a single critical strain rate exists. We postulate that the change in the coil-stretch transition is due to a modified spring law in confinement. We develop ...[more]