Lomefloxacinium picrate.

ABSTRACT: IN THE CATION OF THE TITLE COMPOUND [SYSTEMATIC NAME: (RS)-4-(3-carb-oxy-1-ethyl-6,8-difluoro-4-oxo-1,4-dihydro-quinolin-7-yl)-2-methyl-piperazin-1-ium 2,4,6-trinitro-phenolate], C(17)H(20)F(2)N(3)O(3) (+)·C(6)H(2)N(3)O(7) (-), the piper-azine ring adopts a slightly distorted chair conformation and contains a protonated N atom. An intra-molecular O-H?O hydrogen bond occurs in the cation. The dihedral angles between the mean planes of the six-atom piperazine ring and the 10-atom fused ring system is 43.3?(5)°. The picrate anion inter-acts with the protonated N atom of an adjacent cation through a bifurcated N-H?(O,O) three-center hydrogen bond. Strong N-H?O hydrogen bonds in concert with weak ?-? stacking inter-actions [centroid-centroid distance = 3.6460?(14)?Å] dominate the crystal packing, creating a two-dimensional network structure along [011].

SUBMITTER: Jasinski JP 

PROVIDER: S-EPMC3051677 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature