Ontology highlight
ABSTRACT:
SUBMITTER: Dorr CR
PROVIDER: S-EPMC3053071 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Dorr Casey R CR Yemets Sergiy S Kolomitsyna Oksana O Krasutsky Pavel P Mansky Louis M LM
Bioorganic & medicinal chemistry letters 20110101 1
Triterpene derivatives were analyzed for anti-HIV-1 activity and for cellular toxicity. Betulinic aldehyde, betulinic nitrile, and morolic acid derivatives were identified to have anti-HIV-1 activity. These derivatives inhibit a late step in virus replication, likely virus maturation. ...[more]