Ontology highlight
ABSTRACT:
SUBMITTER: Rotge JY
PROVIDER: S-EPMC3055616 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Rotge Jean-Yves JY Langbour Nicolas N Guehl Dominique D Bioulac Bernard B Jaafari Nematollah N Allard Michele M Aouizerate Bruno B Burbaud Pierre P
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20091104 3
Many voxel-based morphometry (VBM) studies have found abnormalities in gray matter density (GMD) in obsessive-compulsive disorder (OCD). Here, we performed a quantitative meta-analysis of VBM studies contrasting OCD patients with healthy controls (HC). A literature search identified 10 articles that included 343 OCD patients and 318 HC. Anatomic likelihood estimation meta-analyses were performed to assess GMD changes in OCD patients relative to HC. GMD was smaller in parieto-frontal cortical reg ...[more]