Ontology highlight
ABSTRACT:
SUBMITTER: Franco SJ
PROVIDER: S-EPMC3056352 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Franco Santos J SJ Martinez-Garay Isabel I Gil-Sanz Cristina C Harkins-Perry Sarah R SR Müller Ulrich U
Neuron 20110201 3
Neuronal migration is critical for establishing neocortical cell layers and migration defects can cause neurological and psychiatric diseases. Recent studies show that radially migrating neocortical neurons use glia-dependent and glia-independent modes of migration, but the signaling pathways that control different migration modes and the transitions between them are poorly defined. Here, we show that Dab1, an essential component of the reelin pathway, is required in radially migrating neurons f ...[more]