Ontology highlight
ABSTRACT:
SUBMITTER: Olson RO
PROVIDER: S-EPMC3056540 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Olson Rachel O'Donnell RO Liu Zhiqi Z Nomura Yoshiko Y Song Weizhong W Dong Ke K
Insect biochemistry and molecular biology 20080205 5
Extensive alternative splicing and RNA editing have been documented for the transcript of DmNa(V) (formerly para), the sole sodium channel gene in Drosophila melanogaster. However, the functional consequences of these post-transcriptional modifications are not well understood. In this study we isolated 64 full-length DmNa(V) cDNA clones from D. melanogaster adults. Based on the usage of 11 alternative exons, 64 clones could be grouped into 29 splice types. When expressed in Xenopus oocytes, 33 D ...[more]