Ontology highlight
ABSTRACT:
SUBMITTER: Reti IM
PROVIDER: S-EPMC3058761 | biostudies-literature | 2011 Mar-Apr
REPOSITORIES: biostudies-literature
Reti Irving M IM Xu Jerry Z JZ Yanofski Jason J McKibben Jodi J Uhart Magdalena M Cheng Yu-Jen YJ Zandi Peter P Bienvenu Oscar J OJ Samuels Jack J Willour Virginia V Kasch-Semenza Laura L Costa Paul P Bandeen-Roche Karen K Eaton William W WW Nestadt Gerald G
Comprehensive psychiatry 20100708 2
<h4>Objective</h4>Preclinical and human family studies clearly link monoamine oxidase A (MAOA) to aggression and antisocial personality (ASP). The 30-base pair variable number tandem repeat in the MAOA promoter regulates MAOA levels, but its effects on ASP in humans are unclear.<h4>Methods</h4>We evaluated the association of the variable number tandem repeat of the MAOA promoter with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, ASP disorder (ASPD) traits in a community ...[more]