Ontology highlight
ABSTRACT:
SUBMITTER: Muller M
PROVIDER: S-EPMC3059509 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Müller Martin M Pym Edward C G EC Tong Amy A Davis Graeme W GW
Neuron 20110201 4
Homeostatic signaling systems stabilize neural function through the modulation of neurotransmitter receptor abundance, ion channel density, and presynaptic neurotransmitter release. Molecular mechanisms that drive these changes are being unveiled. In theory, molecular mechanisms may also exist to oppose the induction or expression of homeostatic plasticity, but these mechanisms have yet to be explored. In an ongoing electrophysiology-based genetic screen, we have tested 162 new mutations for gen ...[more]