Ontology highlight
ABSTRACT:
SUBMITTER: Lei X
PROVIDER: S-EPMC3062907 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Lei Xiaoguang X Danishefsky Samuel J SJ
Advanced synthesis & catalysis 20080801 11-12
The highly efficient synthesis of a novel heat shock protein 90 (Hsp90)-based anticancer agent, triazole-cycloproparadicicol (5), is described. The key step involves a fragment coupling using "click chemistry." The preliminary biological evaluation of triazole-cycloproparadicicol is also reported. ...[more]