The probiotic Escherichia coli Nissle 1917 reduces pathogen invasion and modulates cytokine expression in Caco-2 cells infected with Crohn's disease-associated E. coli LF82.
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ABSTRACT:
SUBMITTER: Huebner C
PROVIDER: S-EPMC3067434 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
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The probiotic Escherichia coli Nissle 1917 reduces pathogen invasion and modulates cytokine expression in Caco-2 cells infected with Crohn's disease-associated E. coli LF82.
Huebner Claudia C Ding Yaoyao Y Petermann Ivonne I Knapp Christoph C Ferguson Lynnette R LR
Applied and environmental microbiology 20110211 7
Increased numbers of adherent invasive Escherichia coli (AIEC) have been found in Crohn's disease (CD) patients. In this report, we investigate the potential of the probiotic Escherichia coli Nissle 1917 (EcN) to reduce features associated with AIEC pathogenicity in an already established infection with AIEC reference strain LF82. ...[more]
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