Ontology highlight
ABSTRACT:
SUBMITTER: Lancioni CL
PROVIDER: S-EPMC3068037 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Lancioni Christina L CL Mahan C Scott CS Johnson Denise F DF Walusimbi Maria M Chervenak Keith A KA Nalukwago Sophie S Charlebois Edwin E Havlir Diane D Mayanja-Kizza Harriet H Whalen Christopher C CC Boom W Henry WH
The Journal of infectious diseases 20110401 7
<h4>Background</h4>Human immunodeficiency virus (HIV)-tuberculosis coinfection is associated with heightened immune activation, viral replication, and T cell dysfunction. We compared changes in T cell activation and function between patients receiving concurrent treatment for HIV-tuberculosis coinfection and those receiving treatment for tuberculosis alone.<h4>Methods</h4>HIV-infected adults with tuberculosis and CD4(+) T cell counts >350 cells/mm(3) were randomized to receive tuberculosis treat ...[more]