Ontology highlight
ABSTRACT:
SUBMITTER: Puliti A
PROVIDER: S-EPMC3070555 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Puliti Aldamaria A Rossi Pia Irene Anna PI Caridi Gianluca G Corbelli Alessandro A Ikehata Masami M Armelloni Silvia S Li Min M Zennaro Cristina C Conti Valerio V Vaccari Carlotta Maria CM Cassanello Michela M Calevo Maria Grazia MG Emionite Laura L Ravazzolo Roberto R Rastaldi Maria Pia MP
The American journal of pathology 20110301 3
The metabotropic glutamate (mGlu) receptor 1 (GRM1) has been shown to play an important role in neuronal cells by triggering, through calcium release from intracellular stores, various signaling pathways that finally modulate neuron excitability, synaptic plasticity, and mechanisms of feedback regulation of neurotransmitter release. Herein, we show that Grm1 is expressed in glomerular podocytes and that a glomerular phenotype is exhibited by Grm1(crv4) mice carrying a spontaneous recessive inact ...[more]