Ontology highlight
ABSTRACT:
SUBMITTER: Mannelqvist M
PROVIDER: S-EPMC3070569 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Mannelqvist Monica M Stefansson Ingunn M IM Bredholt Geir G Hellem Bø Trond T Oyan Anne M AM Jonassen Inge I Kalland Karl-Henning KH Salvesen Helga B HB Akslen Lars A LA
The American journal of pathology 20110201 2
The presence of tumor cells entering vascular channels is a prognostic marker for many cancers, including endometrial carcinoma. Vascular invasion is considered to be an early step in the metastatic process and important for the progress of malignant tumors. Here, we investigated the gene expression patterns related to vascular involvement in 57 primary endometrial cancers, using DNA microarray and quantitative PCR techniques. A vascular invasion signature of 18 genes was significantly associate ...[more]