Ontology highlight
ABSTRACT:
SUBMITTER: Meyer-Ficca ML
PROVIDER: S-EPMC3071264 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Biology of reproduction 20100929 2
Sperm chromatin is organized in a protamine-based, highly condensed form, which protects the paternal chromosome complement in transit, facilitates fertilization, and supports correct gene expression in the early embryo. Very few histones remain selectively associated with genes and defined regulatory sequences essential to embryonic development, while most of the genome becomes bound to protamine during spermiogenesis. Chromatin remodeling processes resulting in the dramatically different nucle ...[more]