Ontology highlight
ABSTRACT:
SUBMITTER: Cheung J
PROVIDER: S-EPMC3078554 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Cheung Jonah J Hendrickson Wayne A WA
Current opinion in microbiology 20100310 2
Two-component systems regulate crucial cellular processes in microorganisms, and each comprises a homodimeric histidine kinase receptor and a cytoplasmic response regulator. Histidine kinases, often membrane associated, detect environmental input at sensor domains and propagate resulting signals to catalytic cytoplasmic transmitter domains. Recent studies on the great diversity of sensor domains reveal patterns of domain organization and biochemical properties that provide insight into mechanism ...[more]