Identification of sensory and signal-transducing domains in two-component signaling systems.
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ABSTRACT:
SUBMITTER: Galperin MY
PROVIDER: S-EPMC4445681 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Publications
Identification of sensory and signal-transducing domains in two-component signaling systems.
Galperin Michael Y MY Nikolskaya Anastasia N AN
Methods in enzymology 20070101
The availability of complete genome sequences of diverse bacteria and archaea makes comparative sequence analysis a powerful tool for analyzing signal transduction systems encoded in these genomes. However, most signal transduction proteins consist of two or more individual protein domains, which significantly complicates their functional annotation and makes automated annotation of these proteins in the course of large-scale genome sequencing projects particularly unreliable. This chapter descr ...[more]
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