Ontology highlight
ABSTRACT:
SUBMITTER: Christiansen G
PROVIDER: S-EPMC3080429 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Christiansen Guntram G Yoshida Wesley Y WY Blom Judith F JF Portmann Cyril C Gademann Karl K Hemscheidt Thomas T Kurmayer Rainer R
Journal of natural products 20081021 11
Microcystins (MCs) are toxic heptapeptides found in cyanobacteria and share the common structure cyclo(-d-Ala(1)-l-X(2)-d-isoMeAsp(3)-l-Z(4)-Adda(5)-d-isoGlu(6)-Mdha(7)). The letters X and Z in the general formula above represent a wide range of l-amino acids that occupy positions 2 and 4, respectively. In general the variation in structural variants is due to the exchange of amino acids in position 7, 2, and 4. In the present work we report two homotyrosine (Hty)-containing microcystin variants ...[more]