Ontology highlight
ABSTRACT:
SUBMITTER: Felek S
PROVIDER: S-EPMC3081084 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Microbiology (Reading, England) 20101118 Pt 3
Yersinia pestis genome sequencing projects have revealed six intact uncharacterized chaperone/usher systems with the potential to play roles in plague pathogenesis. We cloned each locus and expressed them in the Δfim Escherichia coli strain AAEC185 to test the assembled Y. pestis surface structures for various activities. Expression of each chaperone/usher locus gave rise to specific novel fibrillar structures on the surface of E. coli. One locus, y0561-0563, was able to mediate attachment to hu ...[more]