Ontology highlight
ABSTRACT:
SUBMITTER: Fang N
PROVIDER: S-EPMC4264472 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Frontiers in microbiology 20141212
The hmsHFRS operon is responsible for biosynthesis and translocation of biofilm matrix exopolysaccharide. Yersinia pestis expresses the two sole diguanylate cyclases HmsT and HmsD and the sole phosphodiesterase HmsP, which are specific for biosynthesis and degradation, respectively, of 3',5'-cyclic diguanosine monophosphate (c-di-GMP), a second messenger promoting exopolysaccharide production. In this work, the phenotypic assays indicates that Y. pestis sRNA HmsB enhances the production of c-di- ...[more]