Unknown

Dataset Information

0

Highly aminated mesoporous silica nanoparticles with cubic pore structure.


ABSTRACT: Mesoporous silica with cubic symmetry has attracted interest from researchers for some time. Here, we present the room temperature synthesis of mesoporous silica nanoparticles possessing cubic Pm3n symmetry with very high molar ratios (>50%) of 3-aminopropyl triethoxysilane. The synthesis is robust allowing, for example, co-condensation of organic dyes without loss of structure. By means of pore expander molecules, the pore size can be enlarged from 2.7 to 5 nm, while particle size decreases. Adding pore expander and co-condensing fluorescent dyes in the same synthesis reduces average particle size further down to 100 nm. After PEGylation, such fluorescent aminated mesoporous silica nanoparticles are spontaneously taken up by cells as demonstrated by fluorescence microscopy.

SUBMITTER: Suteewong T 

PROVIDER: S-EPMC3084371 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

Highly aminated mesoporous silica nanoparticles with cubic pore structure.

Suteewong Teeraporn T   Sai Hiroaki H   Cohen Roy R   Wang Suntao S   Bradbury Michelle M   Baird Barbara B   Gruner Sol M SM   Wiesner Ulrich U  

Journal of the American Chemical Society 20101215 2


Mesoporous silica with cubic symmetry has attracted interest from researchers for some time. Here, we present the room temperature synthesis of mesoporous silica nanoparticles possessing cubic Pm3n symmetry with very high molar ratios (>50%) of 3-aminopropyl triethoxysilane. The synthesis is robust allowing, for example, co-condensation of organic dyes without loss of structure. By means of pore expander molecules, the pore size can be enlarged from 2.7 to 5 nm, while particle size decreases. Ad  ...[more]

Similar Datasets

| S-EPMC7304990 | biostudies-literature
| S-EPMC5452099 | biostudies-literature
2023-12-04 | GSE247020 | GEO
2017-09-23 | GSE98236 | GEO
| S-EPMC6359328 | biostudies-literature
| PRJEB23155 | ENA
| S-EPMC6044978 | biostudies-literature
| S-EPMC7331230 | biostudies-literature
| S-EPMC3544348 | biostudies-literature
| S-EPMC7766291 | biostudies-literature