Ontology highlight
ABSTRACT:
SUBMITTER: Rittenour WR
PROVIDER: S-EPMC3084840 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Rittenour William R WR Chen Ming M Cahoon Edgar B EB Harris Steven D SD
PloS one 20110429 4
The contribution of plasma membrane proteins to the virulence of plant pathogenic fungi is poorly understood. Accordingly, the objective of this study was to characterize the acyl-CoA dependent ceramide synthase Bar1 (previously implicated in plasma membrane organization) in the wheat pathogen Fusarium graminearum. The role of Bar1 in mediating cell membrane organization was confirmed as ΔBAR1 mutants failed to display a distinct sterol-rich domain at the hyphal tip. The ΔBAR1 mutants were non-p ...[more]