Dataset Information

Association of PPAR?2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population.

ABSTRACT: The PPAR?2 gene is a key regulator of both proliferation and preadipocyte differentiation in mammals. Herein its genotype and allele frequencies were analyzed using PCR-SSCP in eight pig breeds (N = 416). Two kinds of polymorphisms of the PPAR?2 gene were detected, including a previously reported shift SNP A177G (Met59Val) in exon 1 and a novel silent mutation G876A in exon 5. The results revealed that European pig breeds carry a higher allele A frequency at the A177G locus and a fixed GG genotype at the G876A locus. Allele A at the G876A locus was only found in Jinhua pigs. The association between haplotype (A177G/G876A) and carcass and meat quality traits was analyzed in a Pietrain x Jinhua F2 population (N = 248). The PPAR?2 gene was found to be significantly associated with backfat thickness at the shoulder (p < 0.05), 6-7(th) ribs (p < 0.01), last rib (p < 0.01), gluteus medius (p <0.05) and ham weight (p < 0.01). Significant effects of different haplotypes on ham weight and backfat thickness at the 6-7(th) ribs, last rib, and gluteus medius were also observed.

SUBMITTER: Chen Z

PROVIDER: S-EPMC3085374 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

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Association of PPARγ2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population.

Chen Zhe Z Zhao Xiaofeng X Jiang Xiaoling X Guo Xiaoling X Lv Zunzhou Z Zhou Hongmei H Xu Ningying N

Genetics and molecular biology 20110101 1

The PPARγ2 gene is a key regulator of both proliferation and preadipocyte differentiation in mammals. Herein its genotype and allele frequencies were analyzed using PCR-SSCP in eight pig breeds (N = 416). Two kinds of polymorphisms of the PPARγ2 gene were detected, including a previously reported shift SNP A177G (Met59Val) in exon 1 and a novel silent mutation G876A in exon 5. The results revealed that European pig breeds carry a higher allele A frequency at the A177G locus and a fixed GG genoty ...[more]

PMID: 21637544

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Dataset Information

Association of PPAR?2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population.

Publications

Association of PPARγ2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population.

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