Ontology highlight
ABSTRACT:
SUBMITTER: Zhu L
PROVIDER: S-EPMC3085951 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Zhu Lei L Wang Huiling H Wang Lin L Wang Ye Y Jiang Kun K Li Cheng C Ma Qingjie Q Gao Shi S Wang Liping L Li Wei W Cai Mingjun M Wang Hongda H Niu Gang G Lee Seulki S Yang Wei W Fang Xuexun X Chen Xiaoyuan X
Journal of controlled release : official journal of the Controlled Release Society 20110202 3
Membrane type-1 matrix metalloproteinase (MT1-MMP) is a key member of the matrix metalloproteinase (MMP) family. It participates in pericellular proteolysis of extracellular matrix (ECM) macromolecules and is essential for many biological and pathological processes, such as tumor development, angiogenesis and metastasis. A ligand that specifically binds to MT1-MMP may facilitate the labeling of this molecule, allow imaging at the cellular and organism levels, and provide a means for targeted dru ...[more]