Dataset Information

Beliefs about cancer and diet among those considering genetic testing for colon cancer.

ABSTRACT:

Objective

To assess beliefs about the role of diet in cancer prevention among individuals considering genetic testing for Lynch Syndrome.

Design

Family-centered, cascade recruitment; baseline assessment of a longitudinal study.

Setting

Clinical research setting.

Participants

Participants were 390 persons, ages 18 and older, including persons with a Lynch Syndrome-associated cancer and suspected of carrying a disease causing mutation, and relatives at risk for inheriting a previously identified mutation.

Main outcome measures

Assess clustering of beliefs about the role of diet in cancer prevention and predictors of class membership.

Analysis

Confirmatory factor analysis; 2-class factor mixture model with binary indicators; multilevel regression analyses, individuals nested within families.

Results

Women endorsed a relationship between diet and cancer prevention more often than men (P < .01). A 2-class model was used where Class 1 indicated less likely to link cancer to diet, and Class 2 indicated more likely. Factors associated with increased odds of membership in Class 1 expressed belief that nothing can prevent cancer (P < .01) and fate attribution (P < .01); Class 2 mentioned personal cancer history (P < .05) and genetic knowledge (P < .01).

Conclusions and implications

Identifying factors associated with a belief in cancer prevention through dietary behaviors can inform targeted interventions.

SUBMITTER: Palmquist AE

PROVIDER: S-EPMC3090483 | biostudies-literature | 2011 May-Jun

REPOSITORIES: biostudies-literature

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Publications

Beliefs about cancer and diet among those considering genetic testing for colon cancer.

Palmquist Aunchalee E L AE Upton Rachel R Lee Seungjin S Panter Abby T AT Hadley Don W DW Koehly Laura M LM

Journal of nutrition education and behavior 20110205 3

<h4>Objective</h4>To assess beliefs about the role of diet in cancer prevention among individuals considering genetic testing for Lynch Syndrome.<h4>Design</h4>Family-centered, cascade recruitment; baseline assessment of a longitudinal study.<h4>Setting</h4>Clinical research setting.<h4>Participants</h4>Participants were 390 persons, ages 18 and older, including persons with a Lynch Syndrome-associated cancer and suspected of carrying a disease causing mutation, and relatives at risk for inherit ...[more]

PMID: 21296025

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Project description:BackgroundGenetic counseling (GC) and genetic testing (GT) for prostate cancer (PCA) is a rapidly growing, affording opportunity for healthy lifestyle promotion in men aligned with cancer survivorship and cancer prevention goals. We conducted a targeted dietary analysis of men undergoing GC/GT for PCA for adherence to the United States Department of Agriculture (USDA) Food Pattern recommendations which align with preventing cancer and recurrences in the Genetic Evaluation of Men (GEM) study at two academic centers to inform future strategies for diet intervention.MethodsParticipants of GEM with PCA or at-risk for PCA completed a structured food frequency questionnaire indicating number of servings consumed per day or per week of fruits, vegetables, red meat, seafood, processed meat, and foods high in saturated fat. Adherence to the USDA recommendations was assessed for the total sample and by PCA status and aggressiveness, family history, and body mass index (BMI) through χ 2 contingency analyses. One-sample t tests were used to compare the dietary behaviors of men to USDA Recommendations. Levels of α were set a priori at P < 0.05.ResultsOf 239 males undergoing GC on the study, surveys were completed by 197 men (82.4%), and complete survey data was available on 113 men (47.3%). By the Centers for Disease Control and Prevention BMI classification, 82.3% of the cohort was overweight (45.1%) or obese (37.2%). GEM participants reported consuming less fruits (P = 0.015), less vegetables ( P < 0.001), less seafood ( P < 0.001), more processed meats ( P < 0.001), and more foods high in saturated fats ( P < 0.001) than recommended.ConclusionA high proportion of men receiving GC/GT for PCA were overweight and/or obese with lack of adherence to national diet recommendations for cancer risk and recurrence, affording a teachable moment and supporting the systematic focus of introducing nutrition intervention during GC to promote survivorship.

Dataset Information

Beliefs about cancer and diet among those considering genetic testing for colon cancer.

Objective

Design

Setting

Participants

Main outcome measures

Analysis

Results

Conclusions and implications

Publications

Beliefs about cancer and diet among those considering genetic testing for colon cancer.

Similar Datasets

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