An archived activation tagged population of Arabidopsis thaliana to facilitate forward genetics approaches.

ABSTRACT:

Background

Functional genomics tools provide researchers with the ability to apply high-throughput techniques to determine the function and interaction of a diverse range of genes. Mutagenized plant populations are one such resource that facilitate gene characterisation. They allow complex physiological responses to be correlated with the expression of single genes in planta, through either reverse genetics where target genes are mutagenized to assay the affect, or through forward genetics where populations of mutant lines are screened to identify those whose phenotype diverges from wild type for a particular trait. One limitation of these types of populations is the prevalence of gene redundancy within plant genomes, which can mask the affect of individual genes. Activation or enh

SUBMITTER: Robinson SJ 

PROVIDER: S-EPMC3091532 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature