Ontology highlight
ABSTRACT:
SUBMITTER: Volk N
PROVIDER: S-EPMC3091858 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
MicroRNAs (miRNAs) are short single-stranded RNA molecules that regulate gene expression. MiRNAs originate from large primary (pri) and precursor (pre) transcripts that undergo various processing steps along their biogenesis pathway till they reach their mature and functional form. It is not clear, however, whether all miRNAs are processed similarly. Here we show that the ratio between pre-miRNA and mature miRNA forms varies between different miRNAs. Moreover, over-expression of several factors ...[more]