Ontology highlight
ABSTRACT:
SUBMITTER: Lan G
PROVIDER: S-EPMC3094069 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Lan Ganhui G Schulmeister Sonja S Sourjik Victor V Tu Yuhai Y
Molecular systems biology 20110301
In bacterial chemotaxis, several types of ligand-specific receptors form mixed clusters, wherein receptor-receptor interactions lead to signal amplification and integration. However, it remains unclear how a mixed receptor cluster adapts to individual stimuli and whether it can differentiate between different types of ligands. Here, we combine theoretical modeling with experiments to reveal the adaptation dynamics of the mixed chemoreceptor cluster in Escherichia coli. We show that adaptation oc ...[more]