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Three-component synthesis of cyclic enaminones via ketene cyclization.

ABSTRACT: Cyclic six-membered enaminones were synthesized from three components (bromodiazoacetone, primary amine, and alkyne) in high yields via aza-Michael addition, Wolff rearrangement, and nucleophilic ketene cyclization.

SUBMITTER: Seki H

PROVIDER: S-EPMC3099226 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature

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Three-component synthesis of cyclic enaminones via ketene cyclization.

Seki Hajime H Georg Gunda I GI

Organic letters 20110401 9

Cyclic six-membered enaminones were synthesized from three components (bromodiazoacetone, primary amine, and alkyne) in high yields via aza-Michael addition, Wolff rearrangement, and nucleophilic ketene cyclization. ...[more]

PMID: 21456588

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