Photochemical cleavage of leader peptides.
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ABSTRACT:
SUBMITTER: Bindman N
PROVIDER: S-EPMC3100556 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Publications
Photochemical cleavage of leader peptides.
Bindman Noah N Merkx Remco R Koehler Robert R Herrman Nicholas N van der Donk Wilfred A WA
Chemical communications (Cambridge, England) 20101102 47
We report a photolabile linker compatible with Fmoc solid phase peptide synthesis and Cu(I)-catalyzed alkyne-azide cycloaddition that allows photochemical cleavage to afford a C-terminal peptide fragment with a native amino terminus. ...[more]
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