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Emergence of NDM-1-producing Enterobacteriaceae in Belgium.

ABSTRACT: Five multidrug-resistant nonclonally related Enterobacteriaceae isolates were recovered in Belgium in 2010 from three patients who had been hospitalized in Pakistan, Montenegro, and Serbia/Kosovo. New Delhi metallo-?-lactamase (NDM-1) was detected in each of the isolates in addition to several extended-spectrum ?-lactamases (CTX-M-15, SHV-12), plasmidic cephalosporinases (CMY-16, CMY-58), rRNA methylases (ArmA, RmtB), and Qnr genes (qnrA6, qnrB1, qnrB2). One patient died from uncontrolled sepsis, while the two others recovered. No secondary cases occurred in any of the hospitals.

SUBMITTER: Bogaerts P

PROVIDER: S-EPMC3101394 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature

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Emergence of NDM-1-producing Enterobacteriaceae in Belgium.

Bogaerts Pierre P Bouchahrouf Warda W de Castro Roberta Rezende RR Deplano Ariane A Berhin Catherine C Piérard Denis D Denis Olivier O Glupczynski Youri Y

Antimicrobial agents and chemotherapy 20110328 6

Five multidrug-resistant nonclonally related Enterobacteriaceae isolates were recovered in Belgium in 2010 from three patients who had been hospitalized in Pakistan, Montenegro, and Serbia/Kosovo. New Delhi metallo-β-lactamase (NDM-1) was detected in each of the isolates in addition to several extended-spectrum β-lactamases (CTX-M-15, SHV-12), plasmidic cephalosporinases (CMY-16, CMY-58), rRNA methylases (ArmA, RmtB), and Qnr genes (qnrA6, qnrB1, qnrB2). One patient died from uncontrolled sepsis ...[more]

PMID: 21444697

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