Ontology highlight
ABSTRACT:
SUBMITTER: Lambermon MH
PROVIDER: S-EPMC310232 | biostudies-literature | 2000 Apr
REPOSITORIES: biostudies-literature
Lambermon M H MH Simpson G G GG Wieczorek Kirk D A DA Hemmings-Mieszczak M M Klahre U U Filipowicz W W
The EMBO journal 20000401 7
Efficient splicing of higher plant pre-mRNAs depends on AU- or U-rich sequences in introns. Moreover, AU-rich sequences present in 3'-untranslated regions (3'-UTRs) may play a role in 3' end processing of plant mRNAs. Here, we describe the cloning and characterization of a Nicotiana plumbaginifolia nuclear protein that can be cross-linked to U-rich intron and 3'-UTR sequences in vitro, and associates with nuclear poly(A)(+) RNA in vivo. The protein, UBP1, strongly enhances the splicing of otherw ...[more]