Ontology highlight
ABSTRACT:
SUBMITTER: Fousteri MI
PROVIDER: S-EPMC310237 | biostudies-literature | 2000 Apr
REPOSITORIES: biostudies-literature
Fousteri M I MI Lehmann A R AR
The EMBO journal 20000401 7
In Schizosaccharomyces pombe, rad18 is an essential gene involved in the repair of DNA damage produced by ionizing radiation and in tolerance of UV-induced DNA damage. The Rad18 protein is a member of the SMC (structural maintenance of chromosomes) superfamily, and we show that, like the other SMC proteins in condensin and cohesin, Rad18 is a component of a high-molecular-weight complex. This complex contains at least six other proteins, the largest of which is Spr18, a novel SMC family member c ...[more]