Ontology highlight
ABSTRACT:
SUBMITTER: Bodar EJ
PROVIDER: S-EPMC3105134 | biostudies-literature | 2011 May-Jun
REPOSITORIES: biostudies-literature
Bodar Evelien J EJ Simon Anna A van der Meer Jos W M JW
Molecular medicine (Cambridge, Mass.) 20110125 5-6
We explored the effects of the oral histone deacetylase (HDAC) inhibitor ITF2357 in patients with autoinflammatory syndrome. In this prospective open-label pilot study, eight patients were enrolled; one patient with tumor necrosis factor receptor-associated periodic syndrome (TRAPS), three patients with hyper-IgD and periodic fever syndrome (HIDS) and four patients with Schnitzler syndrome were closely followed during 90 d of ITF2357 treatment. Three patients with Schnitzler syndrome and one TRA ...[more]