Ontology highlight
ABSTRACT:
SUBMITTER: Wiley DM
PROVIDER: S-EPMC3107371 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Wiley David M DM Kim Jun-Dae JD Hao Jijun J Hong Charles C CC Bautch Victoria L VL Jin Suk-Won SW
Nature cell biology 20110515 6
Angiogenesis, the formation of new blood vessels from pre-existing vessels, is critical to most physiological processes and many pathological conditions. During zebrafish development, angiogenesis expands the axial vessels into a complex vascular network that is necessary for efficient oxygen delivery. Although the dorsal aorta and the axial vein are spatially juxtaposed, the initial angiogenic sprouts from these vessels extend in opposite directions, indicating that distinct cues may regulate a ...[more]