Ontology highlight
ABSTRACT:
SUBMITTER: Brand JP
PROVIDER: S-EPMC3107533 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20110504
The Au(III)-catalyzed cyclization of 2-alkynylanilines was combined in a one-pot procedure with the Au(I)-catalyzed C3-selective direct alkynylation of indoles using the benziodoxolone reagent TIPS-EBX to give a mild, easy and straightforward entry to 2-substituted-3-alkynylindoles. The reaction can be applied to unprotected anilines, was tolerant to functional groups and easy to carry out (RT, and requires neither an inert atmosphere nor special solvents). ...[more]