Ontology highlight
ABSTRACT:
SUBMITTER: Swaminathan S
PROVIDER: S-EPMC3109875 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
International journal of Alzheimer's disease 20110602
Copy number variants (CNVs) are DNA sequence alterations, resulting in gains (duplications) and losses (deletions) of genomic segments. They often overlap genes and may play important roles in disease. Only one published study has examined CNVs in late-onset Alzheimer's disease (AD), and none have examined mild cognitive impairment (MCI). CNV calls were generated in 288 AD, 183 MCI, and 184 healthy control (HC) non-Hispanic Caucasian Alzheimer's Disease Neuroimaging Initiative participants. Afte ...[more]