Ontology highlight
ABSTRACT:
SUBMITTER: Martinez-Arias R
PROVIDER: S-EPMC311081 | biostudies-literature | 2001 Jun
REPOSITORIES: biostudies-literature
Martínez-Arias R R Calafell F F Mateu E E Comas D D Andrés A A Bertranpetit J J
Genome research 20010601 6
We have obtained haplotypes from the autosomal glucocerebrosidase pseudogene (psGBA) for 100 human chromosomes from worldwide populations, as well as for four chimpanzee and four gorilla chromosomes. In humans, in a 5420-nucleotide stretch analyzed, variation comprises 17 substitutions, a 3-bp deletion, and a length polymorphism at a polyadenine tract. The substitution rate on the pseudogene (1.23 +/- 0.22 x 10(-9) per nucleotide and year) is within the range of previous estimates considering ph ...[more]