Ontology highlight
ABSTRACT:
SUBMITTER: Dube Mandishora RS
PROVIDER: S-EPMC6047465 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Papillomavirus research (Amsterdam, Netherlands) 20180430
Human papillomaviruses (HPVs) co-evolve slowly with the human host and each HPV genotype displays epithelial tropisms. We assessed the evolution of intra HPV genotype variants within samples, and their association to anogenital site, cervical cytology and HIV status. Variability in the L1 gene of 35 HPV genotypes was characterized phylogenetically using maximum likelihood, and portrayed by phenotype. Up to a thousand unique variants were identified within individual samples. In-depth analyses of ...[more]