Ontology highlight
ABSTRACT:
SUBMITTER: Chung CH
PROVIDER: S-EPMC3111896 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Chung Christine H CH Pohlmann Paula R PR Rothenberg Mace L ML Burkey Brian B BB Parker Joel J Palka Kevin K Aulino Joseph J Puzanov Igor I Murphy Barbara B
Head & neck 20100722 12
<h4>Background</h4>Recurrent head and neck squamous cell carcinoma (HNSCC) remains a difficult cancer to treat. Here, we describe a patient with HNSCC who had complete response to methotrexate (MTX) after progressing on multiple cytotoxic agents, cetuximab, and AMG-479 (monoclonal antibody against insulin-like growth factor-1 receptor [IGF-1R]).<h4>Methods</h4>The clinical information was collected by a retrospective medical record review under an Institutional Review Board-approved protocol. Fr ...[more]