Ontology highlight
ABSTRACT:
SUBMITTER: Dantas VG
PROVIDER: S-EPMC3115310 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Dantas Vitor G L VG Furtado-Alle Lupe L Souza Ricardo L R RL Chautard-Freire-Maia Eleidi A EA
Genetics and molecular biology 20110401 2
Ghrelin coded by the GHRL gene is related to weight-gain, its deactivation possibly depending on its hydrolyzation by butyrylcholinesterase (BChE) encoded by the BCHE gene, an enzyme already associated with the body mass index (BMI). The aim was to search for relationships between SNPs of the GHRL and BCHE genes with BChE activity, BMI and obesity in 144 obese and 153 nonobese Euro-Brazilian male blood donors. In the obese individuals, a significant association with higher BChE activity, in the ...[more]