Ontology highlight
ABSTRACT:
SUBMITTER: Gomes HJ
PROVIDER: S-EPMC3316951 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Gomes Henrique J P HJ Souza Ricardo L R RL Prevedello Flávia Costa FC Mira Marcelo Távora MT Chautard-Freire-Maia Eleidi A EA
Journal of tropical medicine 20120222
Leprosy is a chronic disease caused by Mycobacterium leprae and affects the skin and the peripheral nervous system. Butyrylcholinesterase is coded by the BCHE gene, and the atypical allele (70G; rs1799807) has been investigated as a leprosy risk factor, with conflicting results. The present study estimated the frequencies of variants of rs1799807 and of five additional SNPs at the BCHE gene or near it: rs1126680, rs1803274, rs2863381, rs4440084, and rs4387996. A total of 167 patients and 150 hea ...[more]