Ontology highlight
ABSTRACT:
SUBMITTER: Tandon N
PROVIDER: S-EPMC3117092 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Tandon Nina N Marsano Anna A Maidhof Robert R Wan Leo L Park Hyoungshin H Vunjak-Novakovic Gordana G
Journal of tissue engineering and regenerative medicine 20110110 6
In vitro application of pulsatile electrical stimulation to neonatal rat cardiomyocytes cultured on polymer scaffolds has been shown to improve the functional assembly of cells into contractile engineered cardiac tissues. However, to date, the conditions of electrical stimulation have not been optimized. We have systematically varied the electrode material, amplitude and frequency of stimulation to determine the conditions that are optimal for cardiac tissue engineering. Carbon electrodes, exhib ...[more]