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(3aR,6S,7aR)-7a-Bromo-2-methyl-sulfonyl-1,2,3,6,7,7a-hexa-hydro-3a,6-ep-oxy-isoindole.

ABSTRACT: In the title compound, C(9)H(12)BrNO(3)S, the two tetra-hydro-furan rings adopt envelope conformations, the pyrrolidine ring adopts a half-chair conformation and the six-membered ring is in a boat conformation. In the crystal, weak inter-molecular C-H?O hydrogen bonds link the mol-ecules into R(2) (2)(8) and R(2) (2)(14) rings along the b-axis direction.

SUBMITTER: Temel E

PROVIDER: S-EPMC3120297 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature

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(3aR,6S,7aR)-7a-Bromo-2-methyl-sulfonyl-1,2,3,6,7,7a-hexa-hydro-3a,6-ep-oxy-isoindole.

Temel Ersin E Demircan Aydın A Arslan Hakan H Büyükgüngör Orhan O

Acta crystallographica. Section E, Structure reports online 20110507 Pt 6

In the title compound, C(9)H(12)BrNO(3)S, the two tetra-hydro-furan rings adopt envelope conformations, the pyrrolidine ring adopts a half-chair conformation and the six-membered ring is in a boat conformation. In the crystal, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into R(2) (2)(8) and R(2) (2)(14) rings along the b-axis direction. ...[more]

PMID: 21754707

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(3aR,6S,7aR)-7a-Bromo-2-[(4-methyl-phen-yl)sulfon-yl]-1,2,3,6,7,7a-hexa-hydro-3a,6-ep-oxy-isoindole.

Project description:In the title compound, C(15)H(16)BrNO(3)S, the boat form of the six-membered ring is almost symmetrical with respect to the ep-oxy bridge. The two five-membered rings generated by the ep-oxy bridge of the six-membered ring adopt envelope conformations, whereas the N-containing five-membered ring adopts a twisted conformation. In the crystal, mol-ecules are linked by C-H⋯O hydrogen bonds.

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(3aR*,6S*,7aR*)-7a-Chloro-6-methyl-2-(4-methyl-phenyl-sulfon-yl)-2,3,3a,6,7,7a-hexa-hydro-3a,6-ep-oxy-1H-isoindole.

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(3aR,6S,7aR)-7a-Chloro-2-[(4-nitro-phen-yl)sulfon-yl]-1,2,3,6,7,7a-hexa-hydro-3a,6-ep-oxy-iso-indole.

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(2S*,3S*,3aS*,6S*,7aR*)-3-Hy-droxy-2-[(2R*,3S*)-3-isopropyl-oxiran-2-yl]-3,6-dimethyl-3,3a,5,6,7,7a-hexa-hydro-1-benzofuran-4(2H)-one.

Project description:In the title compound, C(15)H(24)O(4), the six-membered ring shows a distorted chair conformation and the five-membered ring adopts an envelope conformation with the C atom bearing the methyl and OH groups as the flap. In the crystal, O-H?O hydrogen bonds link the mol-ecules into chains running along the a-axis direction.

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2-[(3S,3aS,5R,8S,8aS)-3,8-Di-methyl-hexa-hydro-1H,4H-3a,8a-ep-oxy-azulen-5-yl]propan-2-ol.

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