Discriminating Lyme neuroborreliosis from other neuroinflammatory diseases by levels of CXCL13 in cerebrospinal fluid.
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ABSTRACT:
SUBMITTER: van Burgel ND
PROVIDER: S-EPMC3122636 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Publications
Discriminating Lyme neuroborreliosis from other neuroinflammatory diseases by levels of CXCL13 in cerebrospinal fluid.
van Burgel N D ND Bakels F F Kroes A C M AC van Dam A P AP
Journal of clinical microbiology 20110302 5
CXCL13 in cerebrospinal fluid (CSF) could be an important component for diagnosing Lyme neuroborreliosis (LNB). Levels of intrathecal CXCL13 were determined for 58 LNB patients and 210 controls; sensitivity was 88% and specificity was 89% (cutoff, 250 pg of CXCL13/ml of CSF). Elevated levels of CXCL13 can aid in the diagnosis of LNB, but levels should be interpreted with care. ...[more]
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