Ontology highlight
ABSTRACT:
SUBMITTER: Meng H
PROVIDER: S-EPMC3125420 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Meng Huan H Yang Sui S Li Zongxi Z Xia Tian T Chen Justin J Ji Zhaoxia Z Zhang Haiyuan H Wang Xiang X Lin Sijie S Huang Connie C Zhou Z Hong ZH Zink Jeffrey I JI Nel Andre E AE
ACS nano 20110512 6
Although the aspect ratio (AR) of engineered nanomaterials (ENMs) is one of the key physicochemical parameters that could determine biological outcome, not much is understood about how AR contributes to shaping biological outcome. By using a mesoporous silica nanoparticle (MSNP) library that has been constructed to cover a range of different lengths, we could demonstrate that the AR of rod-shaped particles determines the rate and abundance of MSNP uptake by a macropinocytosis process in HeLa and ...[more]