Ontology highlight
ABSTRACT:
SUBMITTER: Siemerink MA
PROVIDER: S-EPMC3126369 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Siemerink Marco A J MA Kuit Wouter W López Contreras Ana M AM Eggink Gerrit G van der Oost John J Kengen Servé W M SW
Applied and environmental microbiology 20110218 8
Acetoin reductase (ACR) catalyzes the conversion of acetoin to 2,3-butanediol. Under certain conditions, Clostridium acetobutylicum ATCC 824 (and strains derived from it) generates both d- and l-stereoisomers of acetoin, but because of the absence of an ACR enzyme, it does not produce 2,3-butanediol. A gene encoding ACR from Clostridium beijerinckii NCIMB 8052 was functionally expressed in C. acetobutylicum under the control of two strong promoters, the constitutive thl promoter and the late exp ...[more]