Zorrimidazolone, a bioactive alkaloid from the non-indigenous mediterranean stolidobranch Polyandrocarpa zorritensis.
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ABSTRACT:
SUBMITTER: Aiello A
PROVIDER: S-EPMC3131566 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
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Zorrimidazolone, a bioactive alkaloid from the non-indigenous mediterranean stolidobranch Polyandrocarpa zorritensis.
Aiello Anna A Fattorusso Ernesto E Imperatore Concetta C Irace Carlo C Luciano Paolo P Menna Marialuisa M Santamaria Rita R Vitalone Rocco R
Marine drugs 20110623 6
Chemical analysis of the Mediterranean ascidian Polyandrocarpa zorritensis (Van Name 1931) resulted in the isolation of a series of molecules including two monoindole alkaloids, 3-indolylglyoxylic acid (3) and its methyl ester (4), 4-hydroxy-3-methoxyphenylglyoxylic acid methyl ester (1) and a new alkaloid we named zorrimidazolone (2). The structure of the novel compound 2 has been elucidated by spectroscopic analysis and bioactivity of all compounds has been investigated. Zorrimidazolone (2) sh ...[more]
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